The land was originally donated in Spanish colonial times by philanthropist Francisco Antonio Maciel, who teamed up with Mateo Vidal to establish a hospital and charity.

The actual building is dated to 1825 with the plans of José Toribio (son of Tomás Toribio) and later Bernardo Poncini (wing on the Guaraní street, 1859), Eduardo Canstatt (corner of Guaraní and 25 de Mayo) and Julián Masquelez (1889).

[1] The hospital has a temple, the Charity Chapel, built in Greek style by Miguel Estévez in 1798.

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