Original voices from the first film — Sandler, Andy Samberg, Selena Gomez, Kevin James, David Spade, Steve Buscemi, Molly Shannon, Fran Drescher, Rob Riggle, Sadie Sandler, Jonny Solomon, Luenell, Chris Parnell, and Jon Lovitz — returned for the sequel, with Keegan-Michael Key replacing CeeLo Green as Murray.

A year after the wedding, Mavis reveals to Drac that she is pregnant and later gives birth to a baby boy whom the couple name Dennis, nicknamed “Denisovich” by Dracula.

Noticing the potential dangers her son might face living in Transylvania, Mavis starts to consider moving to Johnny's hometown in Santa Cruz, California in order to give Dennis a more “normal” childhood, much to Drac's disapproval.

However, Johnny then discovers a video of Dennis falling that was filmed by the campers, and he and a furious Mavis go back to Transylvania, with Drac and his friends reaching the hotel at the same time.

With Dennis finally embracing his vampire abilities, Johnny and Mavis decide to continue raising him in Transylvania, and they resume the party with his friends and family.

[17] On March 12, 2014, it was announced that Tartakovsky would return to direct the sequel, even though he was originally too busy due to his developing an adaptation of Popeye,[18][19] which would later get shelved.

It was suggested by director Genndy Tartakovsky that Adam Sandler had more creative control over this film than its predecessor, and that at times he was difficult to work with.

[36] According to Rentrak's PostTrak reports, 23% of the audience bought tickets because it was an animated film, while 16% were attracted to the toon's subject matter and plot.

While the China figures are low in comparison to recent Hollywood movie openings, it actually excelled the first film's local lifetime gross by 19% in just the first six days.

Its critical consensus reads, "Hotel Transylvania 2 is marginally better than the original, which may or may not be enough of a recommendation to watch 89 minutes of corny, colorfully animated gags from Adam Sandler and company.

[30] Max Nicholson of IGN awarded it a score of 6.5 out of 10, saying "While Genndy Tartakovsky's animation is top-notch, Hotel Transylvania 2 doesn't live up to the first monster mash.

"[47] Nick Schager of Variety gave the film a negative review, saying "Its plot comes across as just a rickety skeleton designed to prop up Sandler and company's litany of cornball punchlines and gags, only a few of which cleverly play-off of these characters' iconography"[48] Alonso Duralde of The Wrap gave the film a positive review, saying "Whereas the jokes in the Grown Ups series feel reactionary and bullying, the family-friendly Hotel Transylvania gags instead come off as clever and humane, even when they're making fun of helicopter moms and lawsuit-sensitive summer camps.

"[49] Stephen Whitty of the Newark Star-Ledger gave the film one and a half stars out of four, saying "Great movies like ParaNorman and Frankenweenie showed the laughs you could get out of funny fiends; Hotel Transylvania 2 just digs up a few corny gags.

"[51] Peter Hartlaub of the San Francisco Chronicle gave the film one out of four stars, saying "Hotel Transylvania 2 is an unfortunate throwback to about 20 years ago, when animated movies were more widely accepted as cinematic babysitters.

Club gave the film a C+, saying "It's an episodic, energetically animated gag factory from the pen of Adam Sandler, and while it's the best screenplay to bear his name in years, it also warps some overfamiliar family-movie concerns until they become unavoidable in their ickiness.

"[54] Michael Rechtshaffen of The Hollywood Reporter gave the film a positive review, saying "This time around, greater attention has been paid to story and character development (while scaling back on all the sight gags) and the substantial results give the ample voice cast and returning director Genndy Tartakovsky more to sink their teeth into, with pleasing results.

"[55] Josh Kupecki of The Austin Chronicle gave the film one out of five stars, saying "Channeling your inner child, you may find solace in Hotel Transylvania 2, but in the end it has no bite, doing continued disservice to the Universal monsters it scabs out, and adding another soiled feather to Sandler's cap of mediocrity.

[67][68] Adam Sandler, Selena Gomez, and Andy Samberg also reprised their previous roles as Drac, Mavis and Johnny in the film, which was written by Austin Powers writer Michael McCullers.