Upon the revolt instigated by the Wettin margrave Dedi I in 1069, Emperor Henry IV appointed the loyal House of Mansfeld counts (Grafen) in the Saxon Hassegau at Eisleben.
In the 15th century, the primary house divided into cadet branches: Hinterort, Mittelort, and Vorderort, while their County of Mansfeld in 1512 joined the Upper Saxon Circle as an immediate Imperial estate.
Things worsened with the Protestant Reformation: While Count Hoyer VI of Mansfeld-Vorderort (1477-1540) remained a loyal supporter of the Catholic faith, the Mittelort and Hinterort branches sided with Martin Luther.
The male Mansfeld-Vorderort line finally became extinct in 1780 with the death of Josef Wenzel Nepomuk, Prince of Fondi in Italy,[1] and their fiefs fell back to the Electorate of Saxony and the Prussian Duchy of Magdeburg.
In 1771 she had married Prince Franz de Paula Gundaker von Colloredo (1731–1807), last Vice Chancellor of the Holy Roman Empire from 1789, thereby establishing the House of Colloredo-Mansfeld, which claimed headship over the family after the German mediatization.