From 1990–1993 he worked as a director for Armenian State TV and Radio Committee.

From 1993–1998 he was the head of TV Programs Unit of Information and Propaganda Department at Ministry of Defence.

From 1999–2011 Keshishyan produced and directed many TV programs and shows at Armenian Public TV and Nor Alik, such as "Late Night", "Rubicon", "The First Wave Cafe", "The First Program", "National Music Channel", "News on National Music Channel", "Musical Post", "Fashion", "Open project", "Foreign games", "Resolution", "Europolis", "Top 10", "Hot 10", "Two Stars", "Benefis", "Saturday Evering", and "Song of Songs".

In 2010 he was the chief advisor to the President of Public Council of TV and Radio of Armenia.

Hrachya Keshishian is a winner of numerous local and international awards for his films and music videos.