Hrtkovci (Serbian Cyrillic: Хртковци) is a village located in the municipality of Ruma, Serbia.

In 1848–1849, the village was part of autonomous Serbian Vojvodina, but was returned to the jurisdiction of the Military Frontier in 1849.

According to the ethnographic map of the Austrian Monarchy, created by Karl Freiherrn von Czoernig and published in Vienna in 1855, the village of Hrtkovci was predominantly populated by ethnic Albanians.

From 1941 to 1944, the village was under Axis occupation and was included into the Nazi-Puppet Pavelić's Independent State of Croatia, where committed genocide against Serbs, Jews, and Romani People.

According to the MICT verdict against Serbian Radical Party leader Vojislav Šešelj, he came to this village in May 1992 and gave an inflammatory speech calling for the expulsion of Croats from the area and reading a list of individual Croat residents who should leave for Croatia.

On 11 April 2018, the Appeals Chamber of the MICT sentenced Šešelj to 10 years in prison under Counts 1, 10, and 11 of the indictment for instigating deportation, persecution (forcible displacement), and other inhumane acts (forcible transfer) as crimes against humanity due to his speech in Hrtkovci on 6 May 1992, in which he called for the expulsion of Croats from Vojvodina.