The school is part of the Oxnard Union High School District and serves students in the southern portion of the city of Oxnard and most of Port Hueneme including part of Naval Base Ventura County.

On June 4, 2016, during that year's election season, U.S. presidential candidate Hillary Clinton held a campaign rally inside the school's gymnasium.

[2] Hueneme High School has hosted a Navy JROTC program since 1993.

[3] Hueneme High School athletic teams are nicknamed the Vikings.

The school is a charter member of the Citrus Coast League, a conference within the CIF Southern Section (CIF-SS) that was established in 2018.