It serves a portion of northeast Oxnard (including the neighborhood of RiverPark) and western Camarillo as well as the unincorporated communities of El Rio, Strickland, and Nyeland Acres.

Such funding includes U.S. Environmental Protection Agency (EPA) grants that are routinely awarded to California pesticide regulators in millions of dollars.

[5] Plaintiffs in the case argue that California pesticide regulators violated Title VI by approving permits for toxins that disproportionately impacted Latino schoolchildren, who attended schools adjacent to fields with the highest methyl bromide levels in the state.

The Rio Mesa football team won its first CIF-SS championship in 1971 under coach John Reardon, defeating Paso Robles High School 28–20 in the Division A title game.

[11] Rio Mesa won a boys' soccer championship in 2009, beating Pacific View League rival Channel Islands High School 2–1 after a fourth-place finish in the conference.

[17] Jones also won multiple state titles while at Rio Mesa and later after transferring to Thousand Oaks High School, including both sprints four years in a row.