Hughes (Hut’odlee Kkaakk’et in Koyukon) is a city in Yukon-Koyukuk Census Area, Alaska, United States.

According to the United States Census Bureau, the city has a total area of 3.1 square miles (8.0 km2), all of it land.

The majority of the town's population are ethnic Koyukon, Alaskan Athabaskans.

Some of the town's population, as of the 1970s, spoke the Central Dialect of the Koyukon language.

The racial makeup of the city was 5.88% White, 89.41% Native American, and 4.7% from two or more races.