The Tudor Revival building was originally built as a private residence in 1896 by New York architecture firm Renwick, Aspinwall, and Russell.

It sat unoccupied until 1919, when the Garret Family lent the house to the Red Cross as an institution for blinded servicemen in World War I.

[1][2][3] In 1921, the Jesuits from Loyola College purchased the house and 20 surrounding acres from the Garret Family to relocate their campus from Calvert Street.

[1] In 1992, Loyola undertook a $6 million renovation to Jesuit House to consolidate 16 academic departments into a newly converted Humanities Center.

[5] In 2011, the popular Netflix drama series House of Cards filmed scenes inside the Humanities Center.