Humphrey Llwyd (also spelled Lhuyd) (1527–1568) was a Welsh cartographer, author, antiquary and Member of Parliament.

He married into the family of the Llwyd's of Aston, the probable source where his descendants derived their name, as well as their extraction from Einion Evell of the 12th Century.

It has been suggested that he promoted passage of the act requiring the translation of the Bible into Welsh,[1] but no evidence has been found to support that claim.

[1] In 1567, when Llwyd returned to Denbigh, he was given a stipend from the Crown to create the first printed map of Wales for the Dutch geographer Ortelius, for inclusion in his forthcoming Theatrum Orbis Terrarum.

In 2019, Llwyd was the subject of a major exhibition, "Inventor of Britain", at the National Library of Wales, Aberystwyth.