[12] After a successful partnership on the Mud Hens Stadium (Fifth Third Field), the Lucas County Commissioners teamed with HNTB Architecture Inc., a national sports architecture firm located in Kansas City; The Collaborative Inc., of Toledo; and Poggemeyer Design Group, of Toledo, for a new arena.

The arena's location near mass transit systems, use of a light-colored roof membrane to reflect heat and sunlight, and underground cisterns collecting rain water to re-use for landscaping purposes around the arena, are also emphasized to earn LEED points for the project.

The arena is part of a complex that includes SeaGate Convention Centre and Fifth Third Field.

Other performances that have happened at the Huntington Center include: Janet Jackson, Daughtry, Tool, Lil' Wayne, Rascal Flatts, Carrie Underwood, Elton John, Brad Paisley, Stevie Nicks, Kid Rock, Jason Aldean, Hunter Hayes, Bob Seger, Trans-Siberian Orchestra, TobyMac, Snoop Dogg, Wiz Khalifa, Ying Yang Twins, & Disturbed.

All Elite Wrestling debuted in Toledo with AEW Collision on Saturday, October 14, 2023.