The tropical cyclone led to flooding in New Orleans, and broke a drought across the eastern United States.

The system evolved into an extratropical cyclone soon after passing out of the Sunshine State and continued moving east to northeast hugging the Atlantic Seaboard to near the Virginia Capes before moving slowly through the shipping lanes between Canada and Bermuda, blocked by a high pressure system in southeast Canada.

[7] The approach of the hurricane led to the evacuation of 15 aircraft from Florida to Ardmore Air Force Base, in Oklahoma.

[9] Several hundred active wells went out of service, and drilling came to a halt for a few days during and after the cyclone's passage.

One of Humble company's tenders saw three-quarters of its mooring chains compromised, which swung it around into an adjacent oil platform, causing $200,000 in damage (1956 USD).

[12] Due to the impact of Flossy on oil refining in the Gulf of Mexico, the American Petroleum Institute formed a committee called Fundamental Research on Weather Forecasting.

Cattle drowned across the region, and crops such as citrus, sugar cane, and pecan were heavily damaged.

[3] Further northeast, rains brought by Flossy helped relieve drought conditions across the Carolinas,[13] and were considered beneficial.

In Virginia, the gas screw vessel Mary Anne was lost at Naval Station Norfolk.

[18] High tides caused by the then-extratropical cyclone led to water 2.5 feet (0.76 m) deep in sections of Norfolk.