Hydrophyllum macrophyllum, commonly known as the hairy waterleaf[1] or largeleaf waterleaf,[2] is a species of plant in the borage family.

It is native to the eastern United States where it is found primarily in the Midwest and Upper South.

[3] Its natural habitat is forests with mesic, rocky, calcareous soil.

[1] It is a perennial that produces cream-colored flowers in late spring.

This Hydrophylloideae article is a stub.