Hygrophila madurensis is a critically endangered aquatic plant in the family Acanthaceae.

It is endemic to Nallakulam in the Alagar Hills of the Eastern Ghats in Madurai district, Tamil Nadu, India.

[1] Balakrishnan and Subramaniam (in J. Indian Bot.

vol.42 on page 411 in 1964), described the genus Santapaua with only one species, namely S.

India: vol.22 in 2009) merged the genus Santapaua with Hygrophila giving this species the name, Hygrophila madurensis.