[5] The specific name uai is a common interjection of surprise and astonishment used by the people from Minas Gerais.

[2] Tadpoles develop in small rivers and are most commonly found under stones.

Young tadpoles have been collected throughout year, suggesting that reproductive activity is continuous and prolonged.

[5] The species' natural habitat is the margins of small streams in secondary gallery forest.

[2] Hylodes uai is a common species within its small known range but potentially threatened by habitat loss.