[1][2] Some extant examples of hypercarnivorous animals include crocodilians, owls, shrikes, eagles, vultures, felids, most wild canids, polar bear, odontocetid cetaceans (toothed whales), snakes, spiders, scorpions, mantises, marlins, groupers, piranhas and most sharks.
The earliest carnivorous mammal is considered to be Cimolestes, which existed during the Late Cretaceous and early Paleogene periods in North America about 66 million years ago.
While the evolution of large size and carnivory may be favored at the individual level, it can lead to a macroevolutionary decline, wherein such extreme dietary specialization results in reduced population densities and a greater vulnerability for extinction.
This indicates that a stronger bone structure is a crucial requirement and drives selection towards predatory hypercarnivore lifestyle in mammals.
[11][12] Positive selection of one gene related to enhanced bone mineralisation has been found in the Scimitar-toothed cat (Homotherium latidens).