Hyperolius drewesi is a species of frog in the family Hyperoliidae.

Common names include Oceanic tree frog and Drewes' reed frog.

It is the only Reed frog found on Príncipe Island.

[1] Hyperolius drewesi is described from 17 males and one female, the male snout-vent range 24.8 – 30.9 mm and the female 32.7 mm.

Juvenile coloration is tan with bright yellow dorsolateral lines.