[3] According to researchers, claims about the existence of hypoallergenic dog breeds may have been fueled by unsubstantiated articles on the internet.
[11] Breeds that shed less are more likely to be hypoallergenic, since the dog's dander and saliva stick to the hair and are not released into the environment.
[12] However, protein expression levels play a major role and amount of shedding alone does not determine degree of allergic reaction.
[16] As noted above, the amount of the allergenic protein present on the dander and in saliva varies by breed, but also by individual.
[17][18] But for most breeds, when not regularly bathed, even a dog who sheds very little or has little dander can trigger a reaction in a sensitive person.
It is possible that the total body surface area of the dog is more indicative of reduced production of allergens than its breed.
[27] Scientific research has repeatedly shown that good cleaning practices in the home remove allergens from the environment.
studies suggesting early introduction of pets to home may reduce the likelihood of developing sensitization.