[1] He was a French Canadian fur trader who eventually settled in Mendota, Minnesota, opened the first general store there,[2] and served as the first treasurer of Dakota County.

Hypolite and Angelique's wedding at Lac qui Parle in 1838 was attended by missionary Stephen Return Riggs,[4] and was later recorded as a Protestant marriage by Monsignor Augustin Ravoux.

[6] In 1848, Dupuis naturalized as an American citizen around the time that Henry Sibley was elected as the at-large Congressional district representative for the Wisconsin Territory.

In 1854, Dupuis built a two-story home made of Wisconsin brick, and operated the first general store and grocery in Mendota from the main floor.

[8] In 1871, Dupuis sold his brick home to Timothy Fee, and moved to the Devil’s Lake Reservation in North Dakota to work as storekeeper for the Fort Totten Indian Agency.