Hypostomus isbrueckeri[1] is a species of catfish in the family Loricariidae.

It is native to South America, where it occurs in the middle and upper Uruguay River basin.

The species reaches 30.8 cm (12.1 inches) in total length, can weigh up to at least 285 g, and is believed to be a facultative air-breather.

Its specific epithet, isbrueckeri, presumably honors Isaäc J. H. Isbrücker, a Dutch ichthyologist known for his contributions to the study of loricariid catfish.

[2][3] This article relating to Hypostominae is a stub.