[3][8] Yarbro has said that throughout his teens and early twenties, he suffered from depression and eating disorders, engaged in self-harm and attempted suicide.

[5] Yarbro has described his motivation for starting his YouTube channel as a response to what he saw as the widespread practice of skin-care companies misinforming consumers about dermatology in order to increase the prices of their products.

[15][16][17] During this period, his videos generated $3.2 million in media impact value for the brand,[15] and reportedly led to an 89% increase in its global sales in 2020.

[19][20] That December, he announced his first product collaboration, the Hyram x Kinship Sea the Good collection, with a portion of the profits donated to Lonely Whale, a charity focused on removing plastic from oceans.

[22] In June 2021, Yarbro launched his skincare product line, Selfless by Hyram, in collaboration with Colette Laxton and Mark Curry, co-founders of The Inkey List.

[11] According to The Washington Post, Yarbro's brand focuses on promoting "clean beauty," emphasizing products with safe, organic ingredients.

[31] The Independent reported that he tends to avoid products containing fragrances and essential oils and prefers brands with sustainable manufacturing practices.

[32] Nylon included excessive slugging in their list of the 10 worst TikTok beauty trends of 2021, citing Yarbro as one of the influencers who promoted it.