It stars Randy Baruh, Noah Bean, Kelly Hutchinson, Charissa Chamorro, Nicholas DeCegli, and Kate Gersten as a group of friends who encounter "lunar radiation" that causes people to go insane.

[1] John Anderson of Variety wrote that it was probably more fun to make than it is to watch, as horror films have already parodied themselves at length.

[2] Bloody Disgusting rated it 4.5/5 stars and wrote, "Hysterical Psycho is by far one of the most absurd films I’ve ever admitted to loving.

"[3] Mark L. Miller of Ain't It Cool News compared it to Student Bodies and wrote, "There are moments that will definitely make you laugh, but in between those guffaws, I found myself mostly impressed by the intensity and creativity of the scares.

"[4] Matt Donato of We Got This Covered rated it 2.5/5 stars and wrote, "It's a shame that Hysterical Psycho never really comes together, because there are some hilariously horrifying moments of spoofy slasher goodness to be found here.