1FG9, 1FYH, 1JRH345915979ENSG00000027697ENSMUSG00000020009P15260P15261NM_000416NM_001363526NM_001363527NM_010511NP_000407NP_001350455NP_001350456NP_034641Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene.

[5][6][7] The gene IFNGR1 encodes IFN-γR1, which is the ligand-binding chain (alpha) of the heterodimeric gamma interferon receptor, which is found on macrophages.

[5] Interferon gamma receptor 1 has been shown to interact with Interferon-gamma.

[8][9] Mutations in the IFNGR1 gene can lead to extreme susceptibility to Mycobacterial infections.

[12][13] This article incorporates text from the United States National Library of Medicine, which is in the public domain.