Fokianaki's exhibitions explore the relation between art, formations of power and how they metamorphose under the influence of geopolitics, national identity and cultural and anthropological histories.

[8] In May 2022, Fokianaki was announced as the artistic director of the festival Survival Kit,[9] organised by the Latvian Center for Contemporary Art, in Riga.

In November 2023, Fokianaki was announced as the new director of Kunsthalle Bern[10] Since 2013 she has showcased at State of Concept, solo exhibitions of artists such as Laure Prouvost,[11] the research agency Forensic Architecture,[12] Croatian artist Sanja Iveković,[13][14] Dutch collective Metahaven,[15] the film collective Rojava Film Commune.

[26][27][28] In 2023, she was the co-curator of Machinations,[29] a large-scale research and exhibition project at Museo Nacional Centro de Arte Reina Sofía.

She has lectured in various institutions on issues that explore how institutional and curatorial practices respond to the current economic and socio-political shifts in the West [14] She writes for various international art journals and publications [35] such as a joint opinion piece on art, economy and documenta's arrival in Athens, written with former Greek Minister of Finance Yanis Varoufakis[36] and an opinion piece around the discussion of looted artefacts and specifically the Parthenon Marbles for frieze (magazine).