The ITV News at 10.30 is a flagship news programme on British television network ITV, broadcast on Monday to Friday at 10:30pm, between 2 February 2004 and 10 January 2008.

The bulletin was a twenty-five-minute broadcast of British national and international news, with a dedicated business, sports, and a review of the following morning' newspaper front pages.

It was followed by a five-minute round-up of news from the ITV regions around the United Kingdom.

The programme was broadcast for the final time in the 10:30pm timeslot on Thursday 10 January 2008, with News at Ten relaunching the following Monday.

On Wednesday 31 October 2007, it was confirmed that ITV was planning to bring back News at Ten, with the presenter Trevor McDonald and former Sky News presenter Julie Etchingham.