Directed, produced, and written by Taryn Southern and Elena Gaby,[3] it featured Bryan Johnson, David Eagleman, Ramez Naam, Tristan Harris, Nita Farahany, and John Donoghue.

[1] I Am Human follows the medical cases of three patients undergoing complex experimental brain treatments with the goal of regaining lost abilities, including body movement and vision.

[4][5][6] The documentary follows Bill, a man who became quadriplegic following a bicycle accident, who successfully had use of his arms and hands restored by a brain implant; Anne, who has Parkinson's disease but had its symptoms managed through technology;[7] and Stephen, who lost his eyesight due to a neurological condition.

[10] The film contains interviews with entrepreneur Bryan Johnson, neuroscientists David Eagleman and John Donoghue, author Ramez Naam, computer scientist Tristan Harris,[11] and professor Nita Farahany.

[18] In a review for The Verge, senior tech and policy editor Adi Robertson considered I Am Human to be "an optimistic, wholesome antidote to fearmongering" that had "a refreshing focus on people".