After the death of his father, in 1868, he resolved the problems related to the division of inheritance that could have resulted in the liquidation of the flourishing enterprise.

[1] The other heirs, his sisters Giuseppina and Angelina, were not interested in the family businesses and preferred the payment of their parts.

[1] Over time he brought the flotilla of the paternal shipping line Societa in Accomandita Piroscafi Postali-Ignazio & Vicenzo Florio (Florio Line) to a hundred units and in 1881 merged with the Rubattino company in Genoa, giving rise to the Navigazione Generale Italiana.

[2] At the time of the merger, the Florio Line was already a major company with a monopoly of the trade in the Mediterranean.

[4] In 1883 he was appointed Senator of the Kingdom of Italy, due to the fact that he had paid three thousand lire of direct taxation for three years because of his assets or industry.