In his university years he came into contact with other young protagonists of the Milanese scene together with whom he took part in the creation of the Italian Modern Movement.
His long professional activity, which began before his graduation at the end of the 1920s with his father Arnaldo Gardella [it] (1873–1928), produced an enormous quantity of projects and realizations.
The figure of Gardella remained at the pinnacle of Italian architecture for all of the 1960s and '70s, with intense professional activity whose importance is proven by his presence in international publications.
Gardella is one of the Italian Rationalists, but his use of local construction techniques, like the famous brick screen of the Dispensario in Alessandria, makes him in some ways a heretic.
But Mario Ridolfi and I said, jokingly, that if we were really the fathers of all the works exhibited (at the 1980 Venice Biennale) we would have to admit (...) to having gone to bed with women of every type and every race."
- Complementing this aspect is his capacity to change registers, to adapt himself to the genius loci (the spirit of a place), as few other architects have succeeded to do.
A list of his publications is available at: Gardella also had an important role in education, from his invitation in 1949 by Giuseppe Samonà to be part of the staff of the IUAV.