[6] The Roman Empress Helena of Constantinople who temporarily resided in nearby Sebastia used to swim in the lake in Ijinsinya with her maids.

Men were forbidden from entering the area by Empress Helena in order to guarantee her and her maids' privacy.

The name Ijnisinya derives from Greek, translating as "the Eden of women" reflecting the original use of the village site.

[5] There is an Ancient Roman building named Sheikh Shu'la that lies atop a hill overlooking three villages, including Ijnisinya as well as, Sebastia, and an-Naqura.

The remains of the monastery include stone closets, a prison, galleys, secret passageways, and several wells.

[6] Ijinsinya's mosque dates back to the days of Umar ibn al-Khattab and is currently part of the village school.

[5] Ijnisinya was among a number of Christian villages settled by Crusaders in the area of Nablus and Sebastia during the 12th century.

[8] In 1596, it appeared in Ottoman tax registers as "Jinisina", a village in the nahiya of Jabal Sami in the liwa of Nablus.

It is adjacently east of Sebastia, northeast of an-Naqura, south of Beit Imrin, north of Zawata, west of Asira Al-Shamaliya[25] Ijnisinya has an elevation of 460 meters above sea level.

Empress Helena built an aqueduct to carry water from Ijnisinya to Sebastia but it fell into ruin during a drought in Palestine.