It is bordered by al-Badhan and Wadi al Far'a to the east, Yasid to the north, and ‘Asira ash Shamaliya to the west and south.

[4] Talluza may be identified with the Samaritan town of "Tur-Luzeh" (Tûr Lôzah),[5] which according to Albright, is Aramaic for "almond mountain".

[9][10] Talluza may be identified with Tira Luzeh where the High Priest Baba Rabba erected a synagogue in the 4th century CE.

[11] North of the village is the shrine of Nabi Yahuda, consisting of relatively new buildings constructed on ancient foundations, that may be derived from the biblical name Ishud.

Robinson further remarked the house of the village's sheikh was "built round a small court in which cattle and horses were stabled.

[18] The PEF's Survey of Western Palestine found in 1882 Talluza to be "A good-sized village, well-built, with a central Sheik's house.

Under the interim Oslo Peace Accords, areas of the West Bank, which Israel occupied in the 1967 Mideast war, were divided into various categories.

[27] Situated on the northern part of Mount Ebal along the slope of a plateau, Talluza has an average elevation of 545 meters (1,788 ft) above sea level.

Talluza is located off the road connecting Nablus with Asira ash-Shamaliya,[11] and nearby localities the latter to the southwest, Yasid to the northwest, Far'a Camp to the northeast and Ein al-Beida to the southeast.

[3] The main families of the village are al-Hashaykeh (which includes al-Fares, al-Awaysah, al-Balateyyeh, al-Badawi, al-Abu Shehadeh), al-Darawsheh, al-Shanableh, as-Salahat, al-Janajreh and al-Barahmeh.