Each episode of the series features songs written and performed by the aforementioned music group, whose official members all starred in the show.

On May 24, 2011, it was announced that the series wouldn't be renewed for a fourth season (which meant a loss of several months of steady employment for the 100 members of the mostly local crew that worked on the show) and that it would end after the remaining episodes of the third season have aired, though the band itself can continue and is open to doing other projects.

They are often aided by Warehouse Mouse, the freeloading, wall-dwelling anthropomorphic mouse, Nina, their spirited and ever-cheerful neighbor, and Knit Knots, Nina's strict uncle who harbors a dislike for things he deems too "exciting."

It is also revealed in the episode from Season 2 "Trouble in Paradise," that Nina is Hawaiian (much like Wendy Calio is in real life).

Guest stars include French Stewart, David DeLuise, and Brian Beacock.