Set with a rectangular plan, it presents on the external fronts arches with double ferrules and splayings on the windows; the total absence of decorative elements marks a clear sign of detachment from Art Nouveau architecture, prevalent in the city at the time.

[5][6] In Piazza Sacro Cuore, behind the museum, the work "Le Fanciulle" by the Pescara artist Franco Summa was installed in May 2021, urban monuments of about 5 meters representing female features.

[9] The 131 works, divided into 100 paintings, 20 serigraphs and 11 sculptures from a donation by Alfonso and Teresita Paglione,[10] contain a selection of different fields of contemporary figurative art and were produced by seventy-three artists of the second half of the twentieth century, belonging to numerous and different stylistic groups and currents, ranging from moral and political rebellion to the fascist dictatorship and from the rhetorical interpretation of the classicism of Italian artists to the experience of the Accademia di San Fernando in Madrid, from which the group of artists of the Spanish Realidad.

[11] The museum's first temporary exhibition, "Andy Warhol and Mario Schifano between Pop Art and Classicism", is hosted on Floor C and includes 101 works by Andy Warhol,[12][13] including serigraphs, prints, photographs, drawings, posters, posters and magazine covers and over three hundred works by the Italian artist Mario Schifano,[14][15] consisting of photographs, canvases and charcoals, also including the pictorial cycle of the "Matres Matutae", the last to have been made by the artist between 1995 and 1996.

[16] As part of the exhibition, the cycle is compared with the pre-Roman statues of the Matres Matutae, which Schifano was inspired by for the realization of the work, obtained on loan from the Campania Provincial Museum of Capua.