The center included reconstructions of American Indian houses and way of life in the United States.
The Department of Anthropology from the University of Oklahoma supervised the construction of the housing units.
Reconstructed dwellings represent many of the tribes from the Southwest and Southern Plains, including Caddo, Southern Cheyenne, Wichita, Pawnee, Navajo, and Apache.
The museum is located on the site of a massacre of the Tonkawa Indians during American Civil War by Shawnees and other tribes.
In addition to the outdoor displays, Indian City USA offered guided tours, Native dancing, Native American arts and crafts, and the Indian City Museum.