Indian childhood cirrhosis is a chronic liver disease of childhood characterised by cirrhosis of the liver[1] associated with the deposition of copper in the liver.
[2][3][4] It primarily affects children of 1–3 years of age and has a genetic predisposition.
It had a very high case fatality in the past,[5] but has eventually become preventable,[citation needed] treatable "with D-penicillamine in the treatment of 85 biopsy proven cases of Indian childhood cirrhosis", according to the Indian Journal of Pediatrics.
[6] "The drug significantly (P< 0.002) reduced the serum and hepatic copper content and simultaneously there was improvement in clinical and symptomatic aspects.
"[6] It remains a part of the differential diagnosis of Wilson's disease.