The Indy Bag Ladies is an activist organization that raises funds for care and treatment for individuals with Acquired Immunodeficiency Syndrome (AIDS) in Indianapolis, Indiana.

Along with fundraising, the Indy Bag Ladies raise awareness of safe sex practices to in order to prevent sexually transmitted infections (STIs), and increase visibility and promote equality for LGBTQ+ individuals in Indiana through education and advocacy.

[4] They decided to put on their own event instead, using brown paper bags to invite participants to tour restaurants and bars in Indianapolis by a chartered bus while dressed in drag.

[6][7] After the visit, Palmer, Walsh, and Johnson decided the Bag Ladies Bus Tour's second year would be a fundraiser for GMHC and an opportunity to spread the word in Indiana about the new disease.

[2][10] While primarily focused on individuals living with HIV/AIDS, the bag ladies have supported other causes like the Cystic Fibrosis Foundation, the Indiana Youth Group, The Coby Palmer Food Pantry, and The Julian Center.

[3] Besides the bus tour, they host other annual events around Indianapolis, such as "Shimmering Shamrocks", "The Stockings Were Hung", Cadillac Barbie's Disco Brunch, and Loud & Proud, among others.