It was produced by ABC Studios and Marvel Television in association with Devilina Productions, and was co-financed by IMAX Entertainment in a deal that gave the series a theatrical premiere.

Filming took place from March to June 2017, at the former Naval Air Station Barbers Point airfield in Kalaeloa, Hawaii and various locations on the island of Oahu.

Mount reprised his role as an alternate version of Black Bolt in Marvel Studios' MCU film Doctor Strange in the Multiverse of Madness (2022).

[9] Buck felt Lockjaw's storylines would "always [be] fairly simple" as a way to ensure the writers "don't try to pretend that he's anything other than" a dog and pull focus from the other characters.

[53] After the film's cancellation, Jed Whedon, executive producer and showrunner on Agents of S.H.I.E.L.D., noted that series had "a little more freedom" and were "able to do a little bit more" with the species going into the fourth season, including the potential of introducing some of the "classic" Inhumans.

[4] In December, Scott Buck, the showrunner for the first season of the Marvel Netflix series Iron Fist, was revealed to also be executive producing and showrunning Inhumans.

[59] Buck felt working with IMAX "gave us a lot more freedom and pushed and encouraged us to think a little bit bigger than we would if it was just a normal network show.

[60] Buck said Inhumans would be "a family drama with one big story leading us through the season" rather than a procedural series like Agents of S.H.I.E.L.D., and though the initial IMAX release was intended to be "something that absolutely stands on its own", he hoped it would "intrigue people enough to make them want to watch the rest of the show".

[64] At the start of March, the series added Serinda Swan as Medusa,[11] Ken Leung as Karnak,[15] Eme Ikwuakor as Gorgon, Isabelle Cornish as Crystal,[16] and Ellen Woglom as Louise.

[27] The set decorations were described as "slightly futuristic yet quaintly old-fashioned", with elements such as Ancient Greek-inspired statues of the Inhumans' ancestors present in the Royal Hall.

[27] Crystal's bedroom was designed to be able to fit Lockjaw, her 2,000-pound (910 kg) dog; because he can teleport, the set's door frames did not have to be sized to the character, but areas such as where he sleeps in her room did.

"[68] Rheon added that the costumes were intended to look strange to the audience to highlight that the Inhumans have been segregated from Earth and human culture for some time.

[69] Filming for Inhumans began by March 5, 2017, in Downtown Honolulu,[70] under the working title Project Next,[71][70] with Jeff Jur serving as cinematographer.

[73] Mark Kolpack, visual effects supervisor on Agents of S.H.I.E.L.D., stated he would not be involved with Inhumans due to his commitments on S.H.I.E.L.D., despite introducing the species on that series.

[83] Buck noted that Medusa's hair was a very difficult process and "takes quite a long time in post to make that effect work",[4] while Grenaudier added that creating Lockjaw and the city of Attilan were also some of the biggest challenges on the series.

He noted that the team was trying to create effects that would hold up on an IMAX screen and be equivalent to those seen in the MCU films but with a television budget and schedule.

Double Negative began work on Lockjaw in early February 2017, starting to design the final look of the character and creating a rough, simplistic version that could be added to completed sequences as further reference.

Marvel gave approval on the final design for Lockjaw in April 2017, during filming of the series' fifth episode, with Double Negative creating a digital model complete with "animatics, muscles and textures".

"[85] Callery wrote an "adventurous" main theme for the series that was featured in the IMAX release, with a "very, very abridged version" used in the television episodes.

include the alien writing associated with the Inhumans on that series, and the blue Terrigen crystals, which were designed to be consistent with their depiction on Agents of S.H.I.E.L.D.

[61] Loeb noted that Hawaii was chosen as the series' setting, in part because Marvel wanted Inhumans to occur in "a contained area" as "a way to minimize its impact on the rest of the MCU".

[94] James Whitbrook of Gizmodo said "some of these costumes work way better than others": Black Bolt "probably comes out the best", Crystal "gets some points for effort", but Medusa looks "like she's trying to do a particularly low-budget cosplay of Game of Thrones' Sansa Stark".

[97] The first public trailer was released on June 29, after footage had leaked online from the upfront reveal,[98] and was met to mainly negative reactions.

[105][108] The Washington Post's Michael Cavna called the marketing for the series at this point "positively awful", noting "the harder the show's sales force tries to scrub the early stench, the more the entire enterprise stinks to some Marvel fans", and that it would need more "positive word of mouth" before its release to entice fans to see the series in IMAX.

[110] Inhumans held the premiere of its first two episodes (totaling 75 minutes) in Los Angeles at Universal CityWalk on August 28, 2017,[111][112] before debuting on 667 IMAX screens in 67 countries on September 1, 2017.

The website's consensus states, "Marvel's Inhumans sets a new low standard for the MCU with an unimaginative narrative, dull design work, weak characters, and disengaging soapy melodrama.

"[133] Brian Lowry of CNN noted, "If the eight-episode Inhumans fails, it could shine a spotlight on the fact Marvel has generally lagged behind" Warner Bros. Television and DC Comics, who produce the Arrowverse series for The CW.

"[89] In his review for the final episode, Entertainment Weekly's Christian Holub felt Inhumans "will probably be forgotten in the greater MCU, though it would be kind of fun to check in on them at some point".

It's just a boring, lifeless slog easily shooting to the top of the list of the worst things the MCU has produced in its near-decade of existence.

[140] Mount reprised his role in the Marvel Studios film Doctor Strange in the Multiverse of Madness (2022), portraying a different version of the character from Earth-838, which is an alternate universe from the main MCU.