Innenstadt-Ost is a district in the eastern center of Karlsruhe, Germany.

The district, along with Innenstadt-West, forms the city center.

Innenstadt-Ost is the oldest district of Karlsruhe and is located in the area of the former Klein-Karlsruhe, a village from which the city of Karlsruhe later developed.

[1][2] Famous buildings located in Innenstadt-Ost are the Karlsruhe Institute of Technology and the Wildparkstadion.