It was the most populous rural community of Baden-Württemberg before being incorporated into Karlsruhe on February 14, 1975.

[2] Neureut is recorded as having been founded in 1260, under the rule of Rudolf I, Margrave of Baden-Baden.

[3][4] In 1699, Frederick VII, Margrave of Baden-Durlach founded a church for 58 families of Huguenot refugees from nearby France.

[3] During World War II, Neureut was heavily damaged by American planes.

After the war, many American military bases were established in Germany, including one in Neureut in 1959.