Ino (Greek: Ἰνώ), renamed Aelia Anastasia (died 593) was the Empress consort of Tiberius II Constantine (r. 578–582) of the Byzantine Empire, and Augusta from 578 until her death.

According to the account of John of Ephesus, Ino came from Daphnudium, possibly the island of Daphnousia off the coast of Bithynia in the Black Sea.

Her husband and daughter both died prior to the conclusion of the marriage contract, and Ino herself married Tiberius instead.

Justin reportedly suffered from temporary fits of insanity and was unable to perform his duties as early as the fall of the important fortress of Dara to Khosrau I of the Sassanid Empire in November 573.

However, East Roman historians such as Evagrius Scholasticus and Menander Protector mention Tiberius as also gaining power.

[7] The Ecclesiastic History of John of Ephesus and the chronicle of Theophanes the Confessor both record that Sophia considered planning to marry Tiberius herself.

According to John of Ephesus, Sophia sent Patriarch Eutychius of Constantinople to Tiberius to convince him to divorce Ino, offering both herself and her adult daughter Arabia as prospective brides for the new Emperor.

Ino arrived safely and her husband arranged for her meetings with Eutychius and members of the Byzantine Senate.

The marriage of Constantina and Maurice took place in autumn 582, in a ceremony was performed by Patriarch John IV of Constantinople and described in detail by Theophylact Simocatta.