In March 2016, she won the Best Lead Actress Award in the 10th Seiyu Awards for her leading roles as Jun Naruse in the box office hit The Anthem of the Heart and as Yuki Takeya in the anime television series School-Live!.
Her other major roles include Jeanne in The Case Study of Vanitas, Noel in Celestial Method, Misaki Sakimiya in Dead Mount Death Play, Beta/Natsume Kafka in The Eminence in Shadow, Chito in Girls' Last Tour, Hestia in Is It Wrong to Try to Pick Up Girls in a Dungeon?, Chino in Is the Order a Rabbit?, Kirarin/Ciel Kirahoshi/Cure Parfait in Kirakira☆Precure A la Mode, Tamaki "Kimari" Mari in A Place Further than the Universe, Itsuki Nakano in The Quintessential Quintuplets, Shoko Makinohara in Rascal Does Not Dream of Bunny Girl Senpai and Rascal Does Not Dream of a Dreaming Girl, and Rem in Re:Zero − Starting Life in Another World.
[3] Around that time, her mother found a magazine advertisement for a voice-acting audition, which she passed.
[5][6] Her first main roles came later in 2014 as Mirai Nazukari in Locodol and Chino Kafū in Is the Order a Rabbit?,[7][8] as well as Jun Naruse in the animated film The Anthem of the Heart.
performed the songs "Daydream Café" and "Poppin Jump", which are used as the series' opening and closing themes, respectively.
[10] In 2015, Minase voiced Hestia in the anime series Is It Wrong to Try to Pick Up Girls in a Dungeon?.
[11] She also played Yuki Takeya in School-Live!,[12] Carol Malus Dienheim in Symphogear GX,[4] and Nekone in Utawarerumono: Itsuwari no Kamen[13] Later that year, she won the Best Lead Actress Award at the 10th Seiyu Awards for her roles as Jun Naruse and Yuki Takeya.
[14] In 2016, she voiced Rem in Re:Zero − Starting Life in Another World and also performed the insert song "Wishing", which was used in the series' eighteenth episode.
[15][16] She also played Shamille Kitra Katvarnmaninik in Alderamin on the Sky, Fuuka Reventon in ViVid Strike!, Mana Asuha in Luck & Logic, and Akane Segawa in And You Thought There Is Never a Girl Online?.
[4][17] In 2017, she voiced Meteora Österreich in Re:Creators,[18] Tapris Sugarbell Chisaki in Gabriel DropOut,[4] Chizuru Takano in Tsuredure Children,[4] and Yoshino Koiwai in Masamune-kun's Revenge.
[21] Minase made her solo music debut in 2015, affiliating with King Records.
[25] On November 25, 2016, Sony Music Artists and King Records announced that they were cancelling several events for her after she received a death threat online.
[27] "Starry Wish" was used as the ending theme song for the anime ViVid Strike!.
was released on January 23, 2019; it peaked at seventh place on the Oricon Weekly Singles Chart.
[40] Minase participated in the selection of songs and also conveys requests for lyrics and composition, and in the production of albums, her opinion is also reflected on the theme and title.
[55] This work includes songs provided to Minase for the first time by Unison Square Garden's Tomoya Tabuchi [ja] and others.
[64] The final performance was held at LaLa arena TOKYO-BAY [ja] for two days, attracted a total of 19,000 spectators.
[65] Since October 2, 2016, through the Nippon Cultural Broadcasting radio station in Tokyo, Minase has been live broadcasting a radio show called the "Inori Minase MELODY FLAG (水瀬いのり MELODY FLAG) [ja]",[66] also nicknamed as MeloFura (メロフラ) for short.