His most well-known characters are Tetsuya Kuroko, the titular protagonist in the anime series Kuroko's Basketball, Giorno Giovanna in JoJo's Bizarre Adventure, Slaine Troyard in Aldnoah.Zero, Yuya Sakaki in Yu-Gi-Oh!

Arc-V, Hakuryu Ren in Magi: The Labyrinth of Magic and Mikaela Hyakuya in Seraph of the End.

He is also known as the Japanese dub voice of Harry Potter in the Harry Potter film series,[1] and Miles Morales in Spider-Man: Into the Spider-Verse and Spider-Man: Across the Spider-Verse.

[2] In February 2014, he launched a singing career with the single "Fantastic Tune".

[6] In February 2017, Ono and Kana Hanazawa confirmed that they were dating during a live stream promoting Hanazawa's album release, after Shūkan Bunshun published allegations about their relationship.