[14][15] Researchers at the institute reported the first high-throughput[16] next-generation sequencing based approach for detection and genetic epidemiology of SARS-CoV-2.

[20] The institute has been instrumental in creating the concept of MegaLabs for COVID-19 testing and genomic surveillance[21] which also provided the genetic epidemiology of states including Kerala,[22] Andhra Pradesh[23] and Maharashtra.

[24] Researchers at the institute also reported the first cases of COVID-19 reinfection in the country[25] apart from identifying a novel clade of SARS-CoV-2 in India named I/A3i.

[29] Researchers at the institute have been instrumental in the development of COVIDSure[30] an Reverse transcription polymerase chain reaction based kit for diagnosis of COVID-19 and now widely used in India and marketed by Trivitron Healthcare.

[32] The institute has also been playing a leading role in the national COVID-19 genomics consortium[33] and maintains the informatics resources and dashboards.

One of the programmes which has been initiated on this front is Genomics for Understanding Rare Disease, India Alliance Network (GUaRDIAN).

[36] In the few years, it has been able to work closely with clinicians in the network to be able to offer proof of principles for the application of Genomics for Precision Medicine.

IGIB was a co-host of the 13th meeting of the Human Genome Organization (HUGO) in 2008, held at Hyderabad International Convention Centre.