Instituto Loyola is a private Catholic coeducational elementary and secondary education institution run by the Society of Jesus in Managua, Nicaragua.

The school shares the mission of the Society of Jesus, "the service of faith and promotion of justice.

In 1964 the entire block north of Santo Domingo was purchased for a new building completed in 1971.

In 1979 the school began operating in two shifts: morning elementary and afternoon secondary.

[4] Instituto Loyola has for years hosted students from Jesuit Prep Dallas for summer service projects.