369316419ENSG00000082781ENSMUSG00000022817P18084O70309NM_002213NM_001354764NM_001354765NM_001354766NM_001145884NM_010580NP_002204NP_001341693NP_001341694NP_001341695NP_001139356NP_034710NP_001391992Integrin beta-5 is a protein that in humans is encoded by the ITGB5 gene.

[5][6] Integrin, beta 5 has been shown to interact with PTK2,[7] Annexin A5[8] and PAK4.

[9] ITGB5 encodes a subunit of integrin that can interact with several alpha chains to form a variety of integrin heterodimers.

It also plays a potential role in intercellular communication during tumor progression and metastasis.

[10] Elevated levels of ITGB5 have been found in patients with autosomal dominant osteopetrosis type II, a rare disease of bones.