The Intercession Altarpiece is a five-panel tempera and gold on panel painting by Gentile da Fabriano, produced during his stay in Florence from 1420 to 1423.

[1] The polyptych was made following da Fabriano's travels to Florence in 1420–1423, while working on his Adoration of the Magi.

The following cleaning attempts were not able to successfully recover the work's legibility, causing it to be considered a lost da Fabriano masterpiece.

The poor state of the panels also raised doubts about the signature of the artist, which was however affirmed by Roberto Longhi and his students.

Bellosi believed that the work was perhaps sent to Florence as a calling card by the painter, as a test of his skill before settling there.