It is the largest international primary and secondary school in Siem Reap.

The International School of Siem Reap (ISSR) has over 300 students aged between 2 and 18 years from over 20 nationalities.

The school adheres to the British National curriculum National Curriculum (England, Wales and Northern Ireland) in primary school and the Cambridge Assessment International Education (CAIE or simply Cambridge) International General Certificate of Secondary Education IGCSE curriculum in high school (secondary school).

French and Chinese modern foreign languages are offered within the school curriculum.

A new Infants and primary school campus was constructed and opened in August 2019 and is located on the Ring Road, Kor Kranh, near the Siem Reap River on the western side.