Interstate 295 (I-295) is a highway which runs eastward and northward bypass of the cities of Richmond and Petersburg in the US state of Virginia.

The highway begins at I-95 exit 46, south of Petersburg in unincorporated Prince George County with two lanes in each direction.

The exit complex features two-lane collector–distributor lanes and runs longer than one mile (1.6 km).

Additionally, as the road's primary purpose is to direct long-distance travel away from Downtown Richmond, control cities on guide signs for the road include cities such as Washington DC, Charlottesville, and Rocky Mount, North Carolina, as destinations.

However, the highway goes to none of those cities, but instead uses such destinations to direct long-distance travelers away from the congested areas in Downtown Richmond and Petersburg.

In the 1990s, Miami, Florida, was also listed as a control city on some guide signs north of Richmond, but these have been removed or changed.