I-435, a loop route of I-35, is 83.02 miles (133.61 km) long and intersects with nearly every other Interstate Highway in the Kansas City area (except for I-635 and I-670).

The section of I-435 from mile marker 63.4 to mile marker 54.2 is designated as the Lamar Hunt Memorial Highway in honor of Lamar Hunt, the founder of the Kansas City Chiefs.

In 1965, the first segment of I-435 was built and opened between I-35 and US 69 (which, at that time, was signed with Metcalf Avenue) near Overland Park, Kansas.

A second segment was opened the same year between I-70 and US 50 in eastern Kansas City, Missouri, but the two were not connected.

The eastern segment of I-435 was extended south to Gregory Boulevard and north past 22nd Street/Route 78 by 1968.