Iola High School is a fully accredited high school located in Iola, Kansas, United States, serving students in grades 9–12.

The current principal is Scott Carson.

The Mustangs compete in the Pioneer League and are classified as a 4A school, by the KSHSAA.

[2] Throughout the history of Iola athletics, the Mustangs have won 3 state championships and the Fillies have won 1 (see table below).

This Kansas school-related article is a stub.