Irah Chase (born at Stratton, Vermont, October 5, 1793; died at Newtonville, Massachusetts, November 1, 1864) was a United States Baptist clergyman.
After laboring as a Baptist missionary in the western part of Virginia, he became in 1818 professor in a new theological school at Philadelphia, which was soon after transferred to Washington, D.C., to become the theological department of the newly chartered Columbian College.
In this office he remained seven years, one of which he spent in Europe, and in 1825 he was prominent in establishing the Newton Theological Institution at Newton Centre, Massachusetts, with which he was connected as professor until 1845, when he resigned, in order to devote himself to theological and literary studies.
During a visit to Europe in 1830 he aided in founding the Baptist mission in France.
He wrote many sermons, essays, and contributions to reviews on questions of church history and doctrine.